queen bee

from The Century Dictionary.

• noun See bee.

from Wiktionary, Creative Commons Attribution/Share-Alike License.

• noun A reproductive female (especially the only one) in a colony of bees.
• noun idiomatic, colloquial The most important or dominant woman in an organisation or situation.

from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.

• noun fertile egg-laying female bee